

Audited annual filings, TTM ratios and consensus forward estimates
Wall Street price targets and rating actions
Revenue disaggregation per 10-K filing
Annual filings (FY) with consensus forward estimates (hatched)
Free float vs. closely held shares
13F institutional holdings are not available in the current data plan.
SEC Form 4 filings
| Date | Insider | Role | Type | Shares @ price | Value |
|---|---|---|---|---|---|
| Oct 6, 26 | Bonvini Ezio | officer: Sr VP, Research & CSO | M-Exempt | 8,000 @ $2.60 | $20.80K |
| Oct 6, 26 |
| Bonvini Ezio |
| officer: Sr VP, Research & CSO |
| M-Exempt |
| 8,000 @ $2.60 |
| $20.80K |
| Aug 19, 26 | Peters Jeffrey Stuart | officer: Senior VP, GC, and Secretary | S-Sale | 31,105 @ $4.15 | $129.1K |
| Aug 17, 26 | Bonvini Ezio | officer: Sr VP, Research & CSO | M-Exempt | 40,000 @ $2.60 | $104.0K |
| Aug 17, 26 | Bonvini Ezio | officer: Sr VP, Research & CSO | M-Exempt | 40,000 @ $2.60 | $104.0K |
| May 19, 26 | O'Brien Federica F. | director | A-Award | 22,000 @ $4.52 | $99.44K |
| May 18, 26 | O'Brien Federica F. | director | M-Exempt | 3,750 | — |
| May 19, 26 | O'Brien Federica F. | director | A-Award | 3,750 | — |
Stock news · updated daily
ROCKVILLE, MD, Oct. 23, 2026 (GLOBE NEWSWIRE) -- MacroGenics, Inc. (NASDAQ: MGNX), a clinical-stage biopharmaceutical company focused on developing innovative antibody-based therapeutics for the treatment of cancer, today announced positive interim data from its Phase 1 study evaluating MGC026, a B7-H3-directed antibody-drug conjugate (ADC), in patients with advanced solid tumors. These Phase 1 data were presented today at the European Society for Medical Oncology (ESMO) 2026 Congress in Madrid, Spain. These results demonstrated durable activity across a broad range of solid tumors, which the Company believes supports expanded development of MGC026 in front-line metastatic squamous cell carcinoma of the head and neck (SCCHN) in combination with pembrolizumab.
ROCKVILLE, MD, Oct. 15, 2026 (GLOBE NEWSWIRE) -- MacroGenics, Inc. (NASDAQ: MGNX), a clinical-stage biopharmaceutical company focused on developing innovative antibody-based therapeutics for the treatment of cancer, today announced that the first patient has been dosed in the Phase 1 study of MGC030, a first-in-class antibody-drug conjugate (ADC) directed against an undisclosed target, in patients with advanced solid tumors. “MGC030 demonstrated encouraging antitumor activity in multiple preclinical models, and we look forward to advancing this product candidate through the Phase 1 study.
Here is how MacroGenics (MGNX) and C4 Therapeutics, Inc. (CCCC) have performed compared to their sector so far this year.
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ROCKVILLE, MD, Sept. 09, 2026 (GLOBE NEWSWIRE) -- MacroGenics, Inc. (Nasdaq: MGNX), a biopharmaceutical company focused on developing innovative antibody-based therapeutics for the treatment of cancer, today announced that Eric Risser, President and CEO of MacroGenics, will present at the H.C. Wainwright 28th Annual Global Investment Conference on Wednesday, September 16, 2026, at 9:30 a.m. ET.
Positive risk/reward with MacroGenics trading at a discount to its $327 million cash position or $5.15/share. Differentiated pipeline includes antibody drug conjugates (ADC), T-cell engagers (TCE), and lorigerlimab, with multiple near-term catalysts to drive potential upside. Gilead's recent activity on multiple TCEs and MacroGenics' negative enterprise value suggest partnership is under appreciated & undervalued.
Bank of America Corp DE increased its stake in shares of MacroGenics, Inc. (NASDAQ: MGNX) by 30.7% during the first quarter, according to its most recent filing with the SEC. The institutional investor owned 2,401,814 shares of the biopharmaceutical company's stock after purchasing an additional 564,094 shares during the period. Bank of America
Here is how MacroGenics (MGNX) and CareDx (CDNA) have performed compared to their sector so far this year.
Reported EPS vs. consensus estimate
| Report date | EPS est. | EPS actual | Surprise | Revenue |
|---|---|---|---|---|
| Aug 13, 2026 | -0.08 | 0.31 | Beat 498.2% | $32.83M |
| May 13, 2026 | -0.57 | -0.58 | Miss -1.8% | $20.77M |
| Mar 9, 2026 | -0.42 | -0.22 | Beat 47.6% | $41.23M |
| Nov 12, 2025 | -0.48 | 0.27 | Beat 156.3% | $72.84M |
| Aug 14, 2025 | -0.59 | -0.57 | Beat 3.4% | $22.24M |
| May 13, 2025 | -0.61 | -0.65 | Miss -6.6% | $13.19M |
SEC EDGAR filings · last 12 months
| Form | Filed | Accepted | Document |
|---|---|---|---|
| 4 | Oct 7, 2026 | 2026-10-07 16:22:58 | View |
| S-8 | Sep 3, 2026 | 2026-09-03 17:18:08 | View |
| 8-K/A | Sep 3, 2026 | 2026-09-03 16:39:01 | View |
| 4 | Aug 20, 2026 | 2026-08-20 18:19:02 | View |
| 4 | Aug 18, 2026 | 2026-08-18 16:19:05 | View |
| 10-Q | Aug 14, 2026 | 2026-08-14 16:19:57 | View |
| SC 13G/A | Aug 14, 2026 | 2026-08-14 10:22:22 | View |
| 8-K | Aug 13, 2026 | 2026-08-13 16:07:52 | View |
| SC 13G/A | Aug 3, 2026 | 2026-08-03 16:18:00 | View |
| SC 13G | Jul 29, 2026 | 2026-07-29 15:19:53 | View |
Proxy statement (DEF 14A) disclosures
TTM vs. 5-year historical average (annual ratios)
| Metric | MGNX | Historical (5Y) / ref | Status |
|---|---|---|---|
| P/E ratio (TTM) | -10.3x | -15.3x · sector 20.7x | Discount |
| Forward P/E (FY26E) | -1.3x | EPS est. -1.76 | Discount |
| Price / Book | 3.4x | 2.9x | Elevated |
| Price / Sales | 0.9x | 5.6x | Discount |
| EV / EBITDA | -0.8x | 50.2x | Discount |
| Return on equity | -31.3% | — | Weak |
| Gross margin | 50.4% | 88.0% | Below hist. |
| Debt / Equity | 0.82 | 0.56 | Moderate |
| Piotroski / Altman Z | 1/9 | Z -4.42 | Distress |
Discounted cash flow model
Current price $2.28
Latest analyst grade actions
| Date | Firm | Action | Previous | New grade |
|---|---|---|---|---|
| Aug 17, 26 | B. Riley Securities | maintain | Buy | Buy |
| Apr 20, 26 | Barclays | maintain | Overweight | Overweight |
| Apr 10, 26 | B. Riley Securities | upgrade | Neutral | Buy |
| Mar 10, 26 | Barclays | maintain | Overweight | Overweight |
| Nov 3, 25 | HC Wainwright & Co. | maintain | Neutral | Neutral |
| Aug 15, 25 | Leerink Partners | maintain | Outperform | Outperform |
| May 20, 25 | B. Riley Securities | maintain | Neutral | Neutral |
| May 14, 25 | Stifel | maintain | Hold | Hold |
| May 14, 25 | Barclays | maintain | Overweight | Overweight |
1255 daily bars · split adjusted
FY2025 · 10-K disclosure
Daily · Wilder smoothing
Classic floor pivots from 2026-10-23
Computed from daily OHLCV bars
| Indicator | Value | Type | Action |
|---|---|---|---|
| RSI (14) | 25.60 | Oscillator | Buy |
| Stochastic %K (14, 3, 3) | 42.17 | Oscillator | Neutral |
| Williams %R (14) | -98.86 | Oscillator | Buy |
| MACD (12, 26, 9) | -0.22 (Hist -0.06) | Oscillator | Strong Sell |
| Average Directional Index (14) | 17.09 (+DI 12.1 / -DI 44.1) | Trend | Neutral |
| EMA 20 | 3.48 | MA | Strong Sell |
| SMA 20 | 3.53 | MA | Strong Sell |
| EMA 50 | 3.74 | MA | Strong Sell |
| SMA 50 | 3.86 | MA | Strong Sell |
| SMA 200 | 3.40 | MA | Strong Sell |