

Audited annual filings, TTM ratios and consensus forward estimates
Wall Street price targets and rating actions
Revenue disaggregation per 10-K filing
Annual filings (FY) with consensus forward estimates (hatched)
602 daily bars · split adjusted
Current price $0.1651
Latest analyst grade actions
| Date | Firm | Action | Previous | New grade |
|---|---|---|---|---|
| May 20, 26 |
Daily · Wilder smoothing
| Freedom Broker |
| upgrade |
| Hold |
| Buy |
| Nov 7, 25 | RBC Capital | maintain | Sector Perform | Sector Perform |
| Sep 16, 25 | Wells Fargo | downgrade | Overweight | Equal Weight |
| Sep 16, 25 | RBC Capital | downgrade | Outperform | Sector Perform |
| Sep 15, 25 | Jones Trading | downgrade | Buy | Hold |
| Sep 15, 25 | LUCID CAPITAL MARKETS | downgrade | Buy | Neutral |
| Sep 15, 25 | Cantor Fitzgerald | downgrade | Overweight | Neutral |
| Sep 15, 25 | Leerink Partners | downgrade | Outperform | Market Perform |
| Sep 15, 25 | HC Wainwright & Co. | downgrade | Buy | Neutral |
Classic floor pivots from 2026-10-23
Computed from daily OHLCV bars
| Indicator | Value | Type | Action |
|---|---|---|---|
| RSI (14) | 14.05 | Oscillator | Buy |
| Stochastic %K (14, 3, 3) | 4.39 | Oscillator | Buy |
| Williams %R (14) | -96.24 | Oscillator | Buy |
| MACD (12, 26, 9) | -0.06 (Hist 0.00) | Oscillator | Buy |
| Average Directional Index (14) | 65.19 (+DI 4.5 / -DI 40.2) | Trend | Strong Sell |
| EMA 20 | 0.23 | MA | Strong Sell |
| SMA 20 | 0.23 | MA | Strong Sell |
| EMA 50 | 0.33 | MA | Strong Sell |
| SMA 50 | 0.37 | MA | Strong Sell |
| SMA 200 | 0.62 | MA | Strong Sell |
FY2025 · 10-K disclosure
Free float vs. closely held shares
13F institutional holdings are not available in the current data plan.
SEC Form 4 filings
| Date | Insider | Role | Type | Shares @ price | Value |
|---|---|---|---|---|---|
| Oct 1, 26 | Yaras Brandon | officer: Chief Financial Officer | A-Award | 410,000 @ $0.30 | $123.0K |
| Oct 1, 26 | Yaras Brandon | officer: Chief Financial Officer | 70,000 @ $3.48 | $243.6K | |
| Oct 1, 26 | Yaras Brandon | officer: Chief Financial Officer | 28,450 @ $2.20 | $62.45K | |
| Oct 1, 26 | Yaras Brandon | officer: Chief Financial Officer | 55,000 @ $1.50 | $82.50K | |
| Oct 1, 26 | Yaras Brandon | officer: Chief Financial Officer | 84,142 @ $3.74 | $314.7K | |
| Oct 1, 26 | Yaras Brandon | officer: Chief Financial Officer | 88,000 | — | |
| May 27, 26 | Schimmel Paul | director | P-Purchase | 100,000 @ $0.4963 | $49.63K |
| May 11, 26 | Coughlin Timothy | director | A-Award | 50,000 @ $0.95 | $47.50K |
TTM vs. 5-year historical average (annual ratios)
| Metric | ATYR | Historical (5Y) / ref | Status |
|---|---|---|---|
| P/E ratio (TTM) | -0.3x | -1.8x · sector 20.7x | Discount |
| Forward P/E (FY26E) | -0.4x | EPS est. -0.41 | Elevated |
| Price / Book | 0.3x | 1.4x | Discount |
| Price / Sales | 85.2x | 358.9x | Discount |
| EV / EBITDA | -0.2x | -1.9x | Discount |
| Return on equity | -95.6% | — | Weak |
| Gross margin | -11967.9% | -86.7% | Above hist. |
| Debt / Equity | 0.23 | 0.14 | Conservative |
| Piotroski / Altman Z | 2/9 | Z -14.21 | Distress |
Discounted cash flow model
SEC EDGAR filings · last 12 months
| Form | Filed | Accepted | Document |
|---|---|---|---|
| 8-K | Oct 16, 2026 | 2026-10-16 16:02:31 | View |
| SC 13G/A | Oct 7, 2026 | 2026-10-07 07:18:47 | View |
| 4 | Oct 1, 2026 | 2026-10-01 16:03:45 | View |
| 3 | Oct 1, 2026 | 2026-10-01 16:02:29 | View |
| 8-K | Sep 24, 2026 | 2026-09-24 07:47:35 | View |
| DEF 14A | Sep 11, 2026 | 2026-09-11 16:06:02 | View |
| PRE 14A | Aug 31, 2026 | 2026-08-31 06:52:42 | View |
| S-8 | Aug 7, 2026 | 2026-08-07 16:09:33 | View |
| 10-Q | Aug 7, 2026 | 2026-08-07 16:07:18 | View |
| 8-K | Aug 7, 2026 | 2026-08-07 16:04:16 | View |
Proxy statement (DEF 14A) disclosures
Stock news · updated daily
SAN DIEGO, Oct. 19, 2026 (GLOBE NEWSWIRE) -- aTyr Pharma, Inc. (Nasdaq: ATYR) (“aTyr” or the “Company”), a clinical stage biotechnology company engaged in the discovery and development of first-in-class medicines from its proprietary tRNA synthetase platform, today announced a research collaboration with Albert Einstein College of Medicine to further the development and testing of ATYR2810, the Company's monoclonal antibody that targets the neuropilin-2 (NRP2) receptor. The collaboration will be led by Bang H.
Findings highlight ATYR0101's potential as a transformative therapy for disrupting the process of chronic tissue fibrosis. ATYR0101 is currently undergoing IND-enabling studies and expects to be advanced into the clinic in 2027.
MeiraGTx (NASDAQ: MGTX - Get Free Report) and aTyr Pharma (NASDAQ: ATYR - Get Free Report) are both small-cap healthcare companies, but which is the better business? We will compare the two companies based on the strength of their earnings, risk, institutional ownership, profitability, valuation, analyst recommendations and dividends. Valuation and Earnings This table compares MeiraGTx and
aTyr Pharma Inc. (NASDAQ:ATYR) secured a formal agreement with the U.S. Food and Drug Administration (FDA) regarding the Phase 3 study protocol for its lead therapeutic candidate, efzofitimod.
Global Phase 3 study will evaluate efzofitimod in patients with pulmonary sarcoidosis with restrictive lung disease utilizing FVC as primary endpoint. Company expects to initiate study-related activities in the fourth quarter of 2026.
SAN DIEGO, Sept. 01, 2026 (GLOBE NEWSWIRE) -- aTyr Pharma, Inc. (Nasdaq: ATYR) (“aTyr” or the “Company”), a clinical stage biotechnology company engaged in the discovery and development of first-in-class medicines from its proprietary tRNA synthetase platform, today provided an update on the expected timing of a response from the U.S. Food and Drug Administration (FDA) related to the protocol the Company submitted in June 2026 for a planned Phase 3 study of efzofitimod in patients with chronic, symptomatic pulmonary sarcoidosis with restrictive lung disease.
Company awaiting comments from FDA by the end of August 2026 on protocol submitted for planned Phase 3 study of efzofitimod in patients with pulmonary sarcoidosis. Workforce reduction of approximately 60% and program prioritization conserves capital and aligns resources on efzofitimod program in ILD.
Reported EPS vs. consensus estimate
| Report date | EPS est. | EPS actual | Surprise | Revenue |
|---|---|---|---|---|
| Aug 7, 2026 | -0.12 | -0.11 | Beat 9.4% | $189.6M |
| May 15, 2026 | -0.16 | -0.11 | Beat 31.3% | — |
| Mar 5, 2026 | -0.18 | -0.14 | Beat 22.2% | — |
| Nov 6, 2025 | -0.20 | -0.26 | Miss -30.0% | $190.0K |
| Aug 7, 2025 | -0.18 | -0.22 | Miss -22.2% | — |
| May 7, 2025 | -0.19 | -0.17 | Beat 10.5% | — |